Inward Current and Conduction Velocity

نویسندگان

  • Stanley Nattel
  • Wuhua Jing
چکیده

Copyright © 1989 American Heart Association. All rights reserved. Print ISSN: 0009-7330. Online ISSN: TX 72514 Circulation Research is published by the American Heart Association. 7272 Greenville Avenue, Dallas, 1989;65;1485-1498 Circ. Res. S Nattel and W Jing inward current and conduction velocity in anesthetized dogs. A quantitative analysis based on the relation between phase 0 Rate-dependent changes in intraventricular conduction produced by procainamide http://circres.ahajournals.org located on the World Wide Web at: The online version of this article, along with updated information and services, is

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Theoretical Study of the Role of the Funny Current (If) and the Background Inward Current (Ib) in Atrioventricular Nodal Conduction

The aim of the study is to theoretically explore the role of If in atrioventricular nodal conduction using computer simulation. The background current, Ib, is another inward current flowing during diastole and this was also investigated. We began with Inada’s model of the rabbit atrioventricular nodal action potential (N-type). There is uncertainty from experiments about the magnitude and prope...

متن کامل

The effects of antiarrhythmic drugs, stimulation frequency, and potassium-induced resting membrane potential changes on conduction velocity and dV/dtmax in guinea pig myocardium.

For one-dimensional propagation, a nonlinear relationship between Vmax and conduction velocity is predicted by cable theory, and, under experimental conditions, Vmax and conduction velocity may change in opposite directions. Using standard microelectrode techniques, we have measured Vmax and conduction velocity in guinea pig papillary muscles exposed to tetrodotoxin and low sodium (agents expec...

متن کامل

Rate - Dependent Changes in Intraventricular Conduction Produced by Procainamide in Anesthetized Dogs

Antiarrhythmic drug effects on maximal upstroke velocity (V^,) are frequency dependent, which implies that the effects of these drugs on conduction should also be rate dependent. Previous in vivo studies have been limited by assumptions about unchanging propagation pathway, and by the empirical use of a first-order recovery model. To explore time-dependent antiarrhythmic drug-induced conduction...

متن کامل

Correlating the Magnitude and Spatial Gradient of Alternans

OF THESIS CORRELATING THE MAGNITUDE AND SPATIAL GRADIENT OF ALTERNANS Electrical restitution has been shown to inaccurately predict the occurrence of alternans of action potential duration. A new method using the spatial gradient of alternans (SGA) is proposed to predict alternans and cardiac electrical stability. A simulated 1-D strand of tissue was used to compare indexes computed from restit...

متن کامل

Marked Activation Delay Caused by Ischemia Initiated After Regional K ' Elevation in In Situ Pig

Background Conduction mediated by the slow inward (Ca2+) current occurs in vitro under specific experimental conditions but has not been documented in ventricular muscle in vivo during regional myocardial ischemia, perhaps because certain constituents of ischemia (including hypoxia and acidosis) may inhibit the Ca2' current in this setting. We hypothesized that slow conduction mediated by the C...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2005